Physiologic characteristics of interest
Minimum and maximum values for physiologic and laboratory variables of interest were collected from the EHR for the first 24 hours of the hospital stay. Physiologic data collected included heart rate, respiratory rate, systolic blood pressure (SBP), temperature, and oxygen saturation20. Laboratory data collected included blood glucose, haematocrit, haemoglobin, blood urea nitrogen (BUN), sodium, pH, white blood cell (WBC) count, creatinine, platelets, bilirubin, and lactic acid20. Estimated glomerular filtration rate (eGFR) was computed using the maximum creatinine value within the 24-hour window21.