5. Conclusion
This study comprehensively explores the epidemiological trends and
genetic variations of RV infections among hospitalized children on
Hainan Island, spanning from before to after the ending of the Dynamic
Zero-COVID Policy. It reveals significant insights into the prevalence,
diversity, and seasonal fluctuations of RV, as well as the impact of
public health policies on these dynamics. Notably, it highlights the
changing dominance among RV strains over time and the specific
susceptibility patterns seen across different age groups, genders, and
conditions like asthma. The study deepens our understanding of RV
circulation and diseases, significantly aiding translational research to
establish relevant infection models. This essential knowledge
facilitates the creation of targeted therapies, particularly aiding
those most vulnerable to RV-induced illnesses.