Across lakes, our analyses indicate that the relative strength of ABA relationships varied with lake characteristics. The coefficient for the effect of epilimnetic TP on chl-a was larger (more positive) for lakes with high mean epilimnetic TP values; the coefficient for the effect of VHOD on DO was larger (more negative) for lakes with large surface area; and the coefficient for the effect of chl-a on VHOD was larger (more positive) for lakes with long residence time (Figure 6). Other ABA feedback relationships were not significantly mediated by any one of our candidate predictors (maximum depth, surface area, mean depth, residence time, and mean concentrations of focal variables).