Past studies have demonstrated that synoptic weather events play an important role in the spatial and temporal variations of atmospheric carbon dioxide ( within and above the boundary layer. In this study, we investigate the spatial variability of column average CO2 dry air mole fraction (XCO2) due to the impact of synoptic-scale transport using retrievals from the Orbiting Carbon Observatory-2 for 66 summer cold frontal cases over the conterminous U.S. and Mexico above 20°N from 2015 to 2019. The results show that cold fronts in summer are in general agreement with data from the Atmospheric Chemistry and Transport (ACT-America) field campaign observations, which are significantly different compared to non-frontal spatial distributions in summer, though with reduced magnitude due to their nature as a column average as opposed to an in situ measurements in the boundary layer and free troposphere.