Abstract: The laser-guided bomb (LGB) is a highly accurate air-to-ground weapon that offers several benefits. Specifically, it has a high hit rate, significant power, and is straightforward to use. Despite these advantages, LGBs are guided by semi-active lasers, which can be affected by atmospheric conditions. As a result, their spatial release region (SRR) is challenging to calculate accurately, particularly in situations with poor visibility or limited field of view. To address this issue, a new method for determining the SRR is proposed, based on a model of the 1.06 μm laser’s transmittance through the atmosphere and the diffuse reflection of the target surface. This approach allows for the calculation of the capture target time of the laser seeker, as well as the starting position of the ballistic space boundary. By utilizing flight test data such as instantaneous velocity, altitude, off-axis angle, and atmospheric visibility, this method can generate a more precise estimate of the SRR. Ultimately, this can improve the accuracy of LGBs in challenging atmospheric conditions by up to 9.2%.