Severe Refractory Hemorrhagic Cystitis after Hematopoietic Cell Transplantation Responds to Recombinant Human Keratinocyte Growth Factor (KGF) - A Case Report and Review of the LiteratureCatherine Hughes1*, Anora Harris1*, Benjamin Watkins1, Muna Qayed1, Suhag Parikh1, Edwin Horwitz1, Elizabeth Stenger1, Kirsten M Williams1, Michelle L Schoettler1

In low- and middle-income countries, malignancies remain underreported due to lack of quality data. This study outlines the histopathological pattern of pediatric solid malignancies in children aged 0-15yrs at the largest referral hospital in Ethiopia. 432 solid malignancies were evaluated. The most common malignancies were Lymphoma (21.8%), Retinoblastoma (19.4%), and Wilms tumor (13.9%). Burkitt lymphoma accounted for 2.1%, despite being the most reported pediatric malignancy in sub-Saharan Africa in published literature. Definitive diagnosis could not be made in 7% of cases, related to the lack of confirmatory testing. The study highlights the need for improvements in diagnostic capabilities in LMIC.