REFERENCES
1. Eigenmann PA, Lack G, Mazon A, et al. Managing Nut Allergy: A Remaining Clinical Challenge. The journal of allergy and clinical immunology In practice. 2017;5(2):296-300.
2. Dobbertin-Welsch J, Staudacher O, Yurek S, et al. Organ-specific symptom patterns during oral food challenge in children with peanut and tree nut allergy. Pediatr Allergy Immunol. 2022;33(5):e13778.
3. Baker MG, Kattan JD. Review of 400 consecutive oral food challenges to almond. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.2019;122(2):189-192.
4. Midun E, Radulovic S, Brough H, Caubet JC. Recent advances in the management of nut allergy. World Allergy Organ J.2021;14(1):100491.
5. Borres MP, Sato S, Ebisawa M. Recent advances in diagnosing and managing nut allergies with focus on hazelnuts, walnuts, and cashew nuts. World Allergy Organ J. 2022;15(4):100641.
6. Ballmer-Weber BK, Lidholm J, Lange L, et al. Allergen Recognition Patterns in Walnut Allergy Are Age Dependent and Correlate with the Severity of Allergic Reactions. The journal of allergy and clinical immunology In practice. 2019;7(5):1560-1567 e1566.
7. Nilsson C, Berthold M, Mascialino B, Orme M, Sjolander S, Hamilton R. Allergen components in diagnosing childhood hazelnut allergy: Systematic literature review and meta-analysis. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. 2020;31(2):186-196.
8. Cabanillas B, Novak N. Effects of daily food processing on allergenicity. Crit Rev Food Sci Nutr. 2019;59(1):31-42.
9. McWilliam VL, Perrett KP, Dang T, Peters RL. Prevalence and natural history of tree nut allergy. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2020;124(5):466-472.
10. Lyons SA, Clausen M, Knulst AC, et al. Prevalence of Food Sensitization and Food Allergy in Children Across Europe. The journal of allergy and clinical immunology In practice.2020;8(8):2736-2746 e2739.
11. Brough HA, Caubet JC, Mazon A, et al. Defining challenge-proven coexistent nut and sesame seed allergy: A prospective multicenter European study. The Journal of allergy and clinical immunology.2019.
12. Andorf S, Purington N, Block WM, et al. Anti-IgE treatment with oral immunotherapy in multifood allergic participants: a double-blind, randomised, controlled trial. The lancet Gastroenterology & hepatology. 2018;3(2):85-94.
13. Andorf S, Purington N, Kumar D, et al. A Phase 2 Randomized Controlled Multisite Study Using Omalizumab-facilitated Rapid Desensitization to Test Continued vs Discontinued Dosing in Multifood Allergic Individuals. EClinicalMedicine. 2019;7:27-38.
14. Enrique E, Pineda F, Malek T, et al. Sublingual immunotherapy for hazelnut food allergy: A randomized, double-blind, placebo-controlled study with a standardized hazelnut extract. Journal of Allergy and Clinical Immunology. 2005;116(5):1073-1079.
15. Van Hoffen E, Peeters KABM, Van Neerven RJJ, et al. Effect of birch pollen-specific immunotherapy on birch pollen-related hazelnut allergy.Journal of Allergy and Clinical Immunology.2011;127(1):100-101.e103.
16. Wang J, Jones SM, Pongracic JA, et al. Safety, clinical, and immunologic efficacy of a Chinese herbal medicine (Food Allergy Herbal Formula-2) for food allergy. Journal of Allergy and Clinical Immunology. 2015;136(4):962-970.e961.
17. Otani IM, Bégin P, Kearney C, et al. Multiple-allergen oral immunotherapy improves quality of life in caregivers of food-allergic pediatric subjects. Allergy, Asthma and Clinical Immunology.2014;10(1).
18. Arasi S, Otani IM, Klingbeil E, et al. Two year effects of food allergen immunotherapy on quality of life in caregivers of children with food allergies. Allergy Asthma Clin Immunol. 2014;10(1):57.
19. Begin P, Dominguez T, Wilson SP, et al. Phase 1 results of safety and tolerability in a rush oral immunotherapy protocol to multiple foods using Omalizumab. Allergy Asthma Clin Immunol. 2014;10(1):7.
20. Begin P, Winterroth LC, Dominguez T, et al. Safety and feasibility of oral immunotherapy to multiple allergens for food allergy.Allergy Asthma Clin Immunol. 2014;10(1):1.
21. Bradatan E, Vandezende LM. Oral Immunotherapy for peanuts/tree nut allergy: study on the benefit/risk ratio in the pediatric age.Allergy: european journal of allergy and clinical immunology.2015;70:283‐284.
22. Elizur A, Appel MY, Nachshon L, et al. Walnut oral immunotherapy for desensitisation of walnut and additional tree nut allergies (Nut CRACKER): a single-centre, prospective cohort study. The Lancet Child and Adolescent Health. 2019;3(5):312-321.
23. Scurlock AM, Rettiganti M, Hiegel AM, et al. Long-term Walnut Oral Immunotherapy Induces Clinically Relevant Treatment Responses in Tree Nut Allergic Children. Journal of Allergy and Clinical Immunology. 2017;139(2).
24. Beitia JM, Vega Castro A, Cardenas R, Pena-Arellano MI. Pru p 3 Sublingual Immunotherapy in Patients with Lipid Transfer Protein Syndrome: Is It Worth? International archives of allergy and immunology. 2021;182(5):447-454.
25. Elizur A, Appel MY, Nachshon L, et al. Cashew oral immunotherapy for desensitizing cashew-pistachio allergy (NUT CRACKER study).Allergy. 2022;77(6):1863-1872.
26. Alonso R, Enrique E, Pineda F, et al. An observational study on outgrowing food allergy during non-birch pollen-specific, subcutaneous immunotherapy. International archives of allergy and immunology.2007;143(3):185-189.
27. Andorf S, Manohar M, Dominguez T, et al. Observational long-term follow-up study of rapid food oral immunotherapy with omalizumab.Allergy Asthma Clin Immunol. 2017;13:51.
28. Andorf S, Manohar M, Dominguez T, et al. Feasibility of sustained response through long-term dosing in food allergy immunotherapy.Allergy, Asthma and Clinical Immunology. 2017;13(1).
29. Crespo JB, Domingo MV, Arauzo NH, et al. Real life study of the use of omalizumab for pediatric patients with multiple food allergies.Allergol Immunopathol (Madr). 2021;49(2):15-22.
30. Fiocchi A, Artesani MC, Riccardi C, et al. Impact of Omalizumab on Food Allergy in Patients Treated for Asthma: A Real-Life Study.The journal of allergy and clinical immunology In practice. 7(6):1901-1909.e1905.
31. Eapen AA, Lavery WJ, Siddiqui JS, Lierl MB. Oral immunotherapy for multiple foods in a pediatric allergy clinic setting. Annals of Allergy, Asthma and Immunology. 2019;123(6):573-581.e573.
32. Moraly T, Pelletier de Chambure D, Verdun S, et al. Oral Immunotherapy for Hazelnut Allergy: A Single-Center Retrospective Study on 100 Patients. The journal of allergy and clinical immunology In practice. 2019.
33. Sabouraud M, Biermé P, André-Gomez SA, et al. Real-life experience with hazelnut oral immunotherapy. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2022;128(4):432-438.
34. Enrique E, Malek T, Pineda F, et al. Sublingual immunotherapy for hazelnut food allergy: A follow-up study. Annals of Allergy, Asthma and Immunology. 2008;100(3):283-284.
35. Lisann L, Song Y, Wang J, et al. Successful prevention of extremely frequent and severe food anaphylaxis in three children by combined traditional Chinese medicine therapy. Allergy, Asthma and Clinical Immunology. 2014;10(1).
36. Rial MJ, Barroso B, Sastre J. Dupilumab for treatment of food allergy. Journal of Allergy and Clinical Immunology: In Practice.2019;7(2):673-674.
37. Sasamoto K, Nagakura KI, Sato S, Yanagida N, Ebisawa M. Low-dose oral immunotherapy for walnut allergy with anaphylaxis: Three case reports. Allergol Int. 2021.
38. Smeekens JM, Bagley K, Kulis M. Tree nut allergies: Allergen homology, cross-reactivity, and implications for therapy. Clinical and Experimental Allergy. 2018;48(7):762-772.
39. Caffarelli C, Mastrorilli C, Santoro A, Criscione M, Procaccianti M. Component-Resolved Diagnosis of Hazelnut Allergy in Children.Nutrients. 2021;13(2).
40. Datema MR, Zuidmeer-Jongejan L, Asero R, et al. Hazelnut allergy across Europe dissected molecularly: A EuroPrevall outpatient clinic survey. The Journal of allergy and clinical immunology.2015;136(2):382-391.
41. Asero R, Piantanida M, Pinter E, Pravettoni V. The clinical relevance of lipid transfer protein. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2018;48(1):6-12.
42. Mori F, Barni S, Liccioli G, Novembre E. Oral immunotherapy (OIT): A personalized medicine. Medicina (Lithuania). 2019;55(10).
43. Barshow SM, Kulis MD, Burks AW, Kim EH. Mechanisms of oral immunotherapy. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2021.
44. Borres MP, Sato S, Ebisawa M. Recent advances in diagnosing and managing nut allergies with focus on hazelnuts, walnuts, and cashew nuts. World Allergy Organ J. 2022;15(4):100641.
45. Brettig T, Dang T, McWilliam V, Peters RL, Koplin JJ, Perrett KP. The Accuracy of Diagnostic Testing in Determining Tree Nut Allergy: A Systematic Review. The journal of allergy and clinical immunology In practice. 2021;9(5):2028-2049 e2022.
46. Labrosse R, Graham F, Caubet JC. Recent advances in the diagnosis and management of tree nut and seed allergy. Curr Opin Allergy Clin Immunol . 2022;22(3):194-201.
47. Midun E, Radulovic S, Brough H, Caubet JC. Recent advances in the management of nut allergy. World Allergy Organ J . 2021;14(1):100491.
48. Chu DK. Tree nut allergy: a systematic review. Curr Opin Pediatr. 2022.
Tables : 4
Figure 1 Legend: PRISMA diagram for study selection