*Allergen exposure/penetration and initiation of alarmin activity occurs at the subacute, acute lesional and chronic lesional stages, but has only been illustrated at the subacute stage to improve readability. AMPs, antimicrobial peptides; CRSwNP, chronic rhinosinusitis with nasal polyps; DC, dendritic cell; EoE, eosinophilic esophagitis; FeNO, fractional exhaled nitric oxide; Ig, immunoglobulin; IL, interleukin; ILC2, type 2 innate lymphoid cell; PGD₂, prostaglandin D2; TARC, thymus- and activation-regulated chemokine; Th, T helper cell; TNFα, tumour necrosis factor alpha; TSLP, thymic stromal lymphopoietin.

Figure 2. Modified Delphi process