Data sources and literature search
A systematic review was done in accordance with the PRISMA 2020 statement.19 The search was conducted in Ovid MEDLINE, Ovid Embase, PubMed, Web of Science, Cochrane library and ClinicalTrials.gov databases from inception until before the 26th of March 2021. The following search terms and strategy was used:” (Peritonsillar Abscess OR quinsy) AND (Penicillin OR Penicillin V OR Phenoxymethylpenicillin OR Clarithromycin OR Clindamycin OR Erythromycin OR Azithromycin OR Monotherapy OR Dual therapy OR Amoxicillin-Potassium Clavulanate Combination OR Co-amoxiclav OR Augmentin OR Metronidazole OR Anti-Bacterial Agents OR Antibiotics OR Anti-Infective Agents OR Antimicrobial OR Anaerobic Bacteria OR Anaerobic OR Macrolide)”. The titles and abstracts from the initial search results were screened independently by two authors (KP and CMM).