Variables
Total (n=526) ICM (n=224) NICM (n=141)
Mixed CMP (n=161)
Age at implant (years) 64±13 66.3±10.9 * 54.4±14.5 69.1±9.6 +, $
Men 432 (82.1) 206 (92) * 94 (66.7) 132 (82) +, $
Diabetes mellitus 173 (33) 100 (44.8) * 19 (13.5) 54 (33.5) +, $
Hypertension 290 (55.1) 139 (62.1) * 51 (36.2) 100 (62.1) $
Chronic lung diseases 45 (8.6) 21 (9.4) * 3 (2.1) 21 (13) $
Chronic kidney disease 91 (17.3) 45 (20.1) * 10 (7.1) 36 (22.4) $
Alcohol abuse 60 (11.4) 0 (0) * 24 (17) 36 (22.4) +
Malignancy 71 (13.5) 6 (2.7) * 16 (11.3) 49 (30.4) +, $
Atrial fibrillation 196 (37.3) 64 (28.6) 43 (30.5) 89 (55.3) +, $
Left ventricle ejection fraction (in %) 35±10.9 32.7±8.3 * 40.9±14.2 32.9±8.6 $
Estimated glomerular filtration rate 81.7±26.8 79±29 * 89±25.7 79.2±23.4 $
Coronary artery disease (≥50% stenosis) 385 (73.2) 224 (100) * 0 (0) 161 (100) $
Percutaneous coronary intervention 117 (30.7) 117 (53.2) * 0 (0) 0 (0) +
Coronary artery bypass surgery 100 (26) 100 (44.8) * 0 (0) 0 (0) +
Syncope 119 (22.6) 39 (17.4) * 45 (31.9) 35 (21.7)
Cardiac arrest 107 (20.3) 46 (20.5) 23 (16.3) 38 (23.6)
NYHA class 2 282 (53.6) 150 (67) * 56 (39.7) 76 (47.2) +, $
NYHA class 3 136 (25.9) 50 (22.3) * 33 (23.4) 53 (32.9)
Secondary prevention 251 (47.7) 126 (56.3) * 54 (38.3) 71 (44.1) +
Betablocker usage 504 (96.4) 215 (96) 133 (95.7) 156 (97.5)
Amiodarone usage 169 (32.3) 85 (37.9) 39 (28.1) 45 (28.1)
ACEi-ARB usage 383 (73.2) 174 (77.7) * 78 (56.1) 131 (81.9) $
Cardiac resynchronisation therapy 121 (23) 48 (21.4) 26 (18.4) 47 (29.2) $
Minimum VT cycle length (milliseconds) 286.8±45.6 282.5±44 297.7±48.7 281.6±43.1
Therapies received 184 (35.7) 88 (41.1) * 41 (29.1) 55 (34.2)
Shocks received 125 (23.7) 61 (27.2) 26 (18.4) 38 (23.6)
Appropriate shocks 86 (16.3) 42 (18.8) 17 (12.1) 27 (16.7)
Inappropriate shocks 39 (7.4) 19 (8.4) 9 (6.4) 11 (6.8)
Median number of therapies 5 (2, 15.8) 4.5 (1, 12) 4 (2, 16) 8 (2, 27)
VT storms 44 (8.3) 18 (8) 14 (9.9) 12 (7.4)
Generator change 96 (18.3) 40 (17.9) 31 (22) 25 (15.5)
Therapies post generator change 34 (34.7) 16 (39) 9 (29) 9 (34.6)
Time-to-first therapy (years) 2.4±2.8 2.4±2.7 2.8±3.4 2±2.3
Time-to first appropriate shock (years) 2.3±2.8 2.4±2.9 2.6±3.5 1.8±1.9
P values <0.05 have been denoted as * for the significant differences between ICM and NICM groups, + for the significant differences between mixed CMP and ICM groups, $ for the significant differences between Mixed CMP and NICM groups Categorical variables have been presented as frequencies (proportions in %), Continuous variables have been presented as mean ± standard deviation with 95% confidence intervals, Medians have been presented as average (25th, 70th percentiles) ICD-Implantable Cardioverter-Defibrillator, ICM- ischemic cardiomyopathy, NICM- nonischemic cardiomyopathy, Mixed CMP- mixed cardiomyopathy, NYHA- New York Heart Association classification, VT- Ventricular tachycardia P values <0.05 have been denoted as * for the significant differences between ICM and NICM groups, + for the significant differences between mixed CMP and ICM groups, $ for the significant differences between Mixed CMP and NICM groups Categorical variables have been presented as frequencies (proportions in %), Continuous variables have been presented as mean ± standard deviation with 95% confidence intervals, Medians have been presented as average (25th, 70th percentiles) ICD-Implantable Cardioverter-Defibrillator, ICM- ischemic cardiomyopathy, NICM- nonischemic cardiomyopathy, Mixed CMP- mixed cardiomyopathy, NYHA- New York Heart Association classification, VT- Ventricular tachycardia P values <0.05 have been denoted as * for the significant differences between ICM and NICM groups, + for the significant differences between mixed CMP and ICM groups, $ for the significant differences between Mixed CMP and NICM groups Categorical variables have been presented as frequencies (proportions in %), Continuous variables have been presented as mean ± standard deviation with 95% confidence intervals, Medians have been presented as average (25th, 70th percentiles) ICD-Implantable Cardioverter-Defibrillator, ICM- ischemic cardiomyopathy, NICM- nonischemic cardiomyopathy, Mixed CMP- mixed cardiomyopathy, NYHA- New York Heart Association classification, VT- Ventricular tachycardia P values <0.05 have been denoted as * for the significant differences between ICM and NICM groups, + for the significant differences between mixed CMP and ICM groups, $ for the significant differences between Mixed CMP and NICM groups Categorical variables have been presented as frequencies (proportions in %), Continuous variables have been presented as mean ± standard deviation with 95% confidence intervals, Medians have been presented as average (25th, 70th percentiles) ICD-Implantable Cardioverter-Defibrillator, ICM- ischemic cardiomyopathy, NICM- nonischemic cardiomyopathy, Mixed CMP- mixed cardiomyopathy, NYHA- New York Heart Association classification, VT- Ventricular tachycardia P values <0.05 have been denoted as * for the significant differences between ICM and NICM groups, + for the significant differences between mixed CMP and ICM groups, $ for the significant differences between Mixed CMP and NICM groups Categorical variables have been presented as frequencies (proportions in %), Continuous variables have been presented as mean ± standard deviation with 95% confidence intervals, Medians have been presented as average (25th, 70th percentiles) ICD-Implantable Cardioverter-Defibrillator, ICM- ischemic cardiomyopathy, NICM- nonischemic cardiomyopathy, Mixed CMP- mixed cardiomyopathy, NYHA- New York Heart Association classification, VT- Ventricular tachycardia