The understanding of Coronavirus disease 2019 (COVID-19) immune dysregulation is evolving. Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with alternations in both innate and adaptive immunity, probably caused by a complex interplay of genetics and environmental exposure with various triggers. A rare hematological complication of SLE as well as recently reported in adult with COVID-19 is thrombotic thrombocytopenic purpura (TTP). We report a pediatric case with features suggestive of multisystem inflammatory syndrome in children (MIS-C) with coronary artery ectasia, TTP, autoimmune hemolytic anemia (AIHA) and thrombocytopenia with new onset SLE as well.

Recurrent Vincristine-induced Fever in a Child with Wilms tumor

Delayed but Successful T Cell Immune Reconstitution Following Umbilical Cord Blood Transplantation Conditioned with Thymoglobulin alone in IL-7Rα-mutated SCID Eman T. Al-Antary, MD1,5, Mary Caverly, CPNP2, Steve Buck3, Sharat Chandra, MD4, Süreyya Savaşan, MD1-3, 5