Figure 5. PCIS passively sensitized with peanut allergic donor plasma before and after peanut oral immunotherapy (OIT) shows change in contraction response
Contraction responses of PCIS passively sensitized with peanut allergic plasma (PA) from a donor prior to peanut OIT, unstimulated, stimulated with peanut extract or an irrelevant allergen (ovalbumin); PCIS passively sensitized with plasma from the same donor after successful peanut OIT (OIT) stimulated with peanut extract or histamine; PCIS passively sensitized with a mix of plasma from before and after successful peanut OIT (PA+OIT mix) at a ratio of 1:3 respectively, stimulated with peanut extract.