Longitudinal Trajectory Characteristics of FTR
Left heart valve surgery can only reduce the afterload, but cannot solve
TA dilation or improve the preload and RV function, and there is still a
possibility of FTR progression in the long
term[6]. In this study, GBTM model, a statistical
method, was adopted to consider FTR information and FTR changes of
multiple measurements, and finally realized the transformation from ”FTR
at a single time point or cumulative FTR level exposure” to ”dynamic FTR
longitudinal trajectory”. According to grouping selection basis of GBTM
model, the study determined three postoperative FTR longitudinal
trajectory groups, namely ”stable group”, ”increasing-slow group” and
”increasing-fast group”. Among them, patients belonging to the ”stable
group” always had a low postoperative FTR level, and no significant
change was observed within 5 years after surgery. Patients in the ”
increasing-slow group” had a continuous worsening of FTR after MVR, and
the severity of FTR was still less than 10.0 cm² at the end of
follow-up. Patients assigned to the ” increasing-fast group” had
relatively large baseline FTR, which continued to rise rapidly after MVR
and deteriorated to severe FTR about 3 years after surgery. Although
there has been no literature discussion on the longitudinal trajectory
of FTR in the past, this study is consistent with the results of
relevant studies in recent years, and FTR of some patients will
deteriorate to varying degrees with the extension of postoperative
time[10].