Hydroa vacciniforme-like lymphoproliferative disorder (HV-LPD) is a rare cutaneous form of Chronic active Epstein-Barr virus (CAEBV) that presents with vesicular lesions induced by sun-exposure. We describe a patient with CAEBV and HV-LPD whose course following hematopoietic stem cell transplantation was complicated by fatal ruptured cerebral artery aneurysm.