Results
Of 112 subjects who completed the study, 21 were from KP and 91 from
CHLA.
Sites were comparable on prevalence of reclassification from CRMS/CFSPID
to CF (~10%). When sites were compared using specific
variables, the difference between CF and CRMS/CFSPID was not significant
(Supplemental Table 1 ); therefore, stratification by site was
not necessary. Site was included, conservatively, as a covariate
throughout analysis to adjust for other possible site differences.
Demographic characteristics of the CF and CRMS/CFSPID groups showed no
significant differences in age, sex, race/ethnicity distribution, BMI,
and weight-for-length percentile (Table 1 ). There were
significant differences in IRT levels, PSA-ever, pancreatic
insufficiency (PI), FEV1/FVC, and CFQ-R social
(Table 1 ). CFTR genotypes are summarized in