Results
Of 112 subjects who completed the study, 21 were from KP and 91 from CHLA.
Sites were comparable on prevalence of reclassification from CRMS/CFSPID to CF (~10%). When sites were compared using specific variables, the difference between CF and CRMS/CFSPID was not significant (Supplemental Table 1 ); therefore, stratification by site was not necessary. Site was included, conservatively, as a covariate throughout analysis to adjust for other possible site differences. Demographic characteristics of the CF and CRMS/CFSPID groups showed no significant differences in age, sex, race/ethnicity distribution, BMI, and weight-for-length percentile (Table 1 ). There were significant differences in IRT levels, PSA-ever, pancreatic insufficiency (PI), FEV1/FVC, and CFQ-R social (Table 1 ). CFTR genotypes are summarized in