Long-Term Clinical Follow-up
Thirty-days mortality was 1.3% (n=1/77). Overall survival during
further follow-up was 70.1% (n=54/77). Observed survival rates for 1-,
2- and 3-years were 90.9%, 68.8% and 57.1%, respectively. Further
follow-up ranged to 7.1 years. Estimated 7-years survival was 20.6 ±
16.1%. Figure 1A depicts the Kaplan-Meier survival curve for
the entire cohort and Figure 1B shows the corresponding
Kaplan-Meier curve grouped by the true-ID without any significant
difference..
Three-years freedom from rehospitalization was 72.7% (n=56/77). Main
cause for rehospitalization were cardiac (n=16/21; 76.2%) and pulmonary
(n=3/21; 14.3%) reasons. During the same period, freedom from
(indication for) reintervention was 93.2% (n=41/44). Herein two
patients presented with a new high grade aortic valve stenosis and one
patient with leaflet thrombosis. All three patients refused the formally
indicated reintervention.