Quality of Life (CFQ-R, Dutch version)30
The Cystic Fibrosis Questionnaire Revised (CFQ-R) is a self-report questionnaire to measure the physical, emotional, and social impact of CF and includes the following twelve domains: physical functioning, emotional functioning, social functioning, role functioning, body image, eating disturbances, treatment burden, health perceptions, respiratory symptoms, digestive symptoms, weight and vitality. In this study two different versions of the CFQ-R, adapted for the age of the patient, were used: CFQ-R 12-13 yrs. and CFQ-R 14-adulthood. This instrument is considered the “gold standard” quality of life measure for CF. It has well-established reliability and validity,31differentiating those with mild, moderate, and severe CF and showing a response to therapeutic interventions.32,33 The Dutch version of the Cystic Fibrosis Questionnaire Revised (CFQ-R) has been shown to have robust internal consistency and psychometric properties.30 Higher scores indicate better quality of life.