The Dutch Gastrointestinal (GI) Symptom Tracker for People with
Cystic Fibrosis: Associations with anxiety, depression and
health-related quality of life
Marieke Verkleij, PhD,1,2,3 Berber Vlieg-Boerstra, RD
PhD,4,5 Geesje H Hofsteenge, RD
PhD,6 Eric Haarman, MD PhD,7 Jos
Twisk, PhD,8 Alexandra L. Quittner,
PhD,9 Tim de Meij, MD PhD10
1 Amsterdam UMC location University of
Amsterdam, Emma Children’s Hospital, Child and Adolescent Psychiatry &
Psychosocial Care, Amsterdam, The Netherlands
2 Amsterdam Reproduction and Development, Child
Development, Amsterdam, The Netherlands
3 Amsterdam Public Health, Health Behaviors & Chronic
Diseases, Amsterdam, The Netherlands
4 OLVG, Department of Paediatrics, Amsterdam, The
Netherlands
5 Rijnstate Allergy Centre, Rijnstate Hospital,
Arnhem, The Netherlands
6 Department of Nutrition and Dietetics, Amsterdam UMC
location University of Amsterdam, Emma Childrens’s Hospital, Amsterdam,
The Netherlands
7 Amsterdam UMC, Department of Pediatric Pulmonology
and Allergy, Emma Children’s Hospital, Amsterdam, The Netherlands
8 Department of Epidemiology and Data Science,
Amsterdam UMC location VUMC, Amsterdam, The Netherlands
9 Joe DiMaggio Cystic Fibrosis, Pulmonary and Sleep
Center, Hollywood, FL, United States
10 Amsterdam UMC, Department of Pediatric
Gastroenterology, Emma Children’s Hospital, Amsterdam, The Netherlands
Corresponding author: Marieke Verkleij, PhD, Pediatric
Psychologist, Amsterdam UMC location University of Amsterdam, Emma
Children’s Hospital, Child and Adolescent Psychiatry & Psychosocial
Care, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. E-mail:
m.verkleij@amsterdamumc.nl.
Funding: This work was supported by the Dutch Cystic Fibrosis
Foundation. The funding source had no role in study design; in the
collection, analysis and interpretation of data; in the writing of the
report; or in the decision to submit the article for publication.
Keywords: cystic fibrosis, gastrointestinal symptoms,
depression, anxiety, quality of life