Statistical analysis
All statistical analyses were performed with IBM SPSS Statistics for
Windows, Version 28. Due to multiple testing, p-values of <0.001
(two-sided) instead of p<0.05 were considered statistically
significant.
Descriptive statistics were used to evaluate and summarize the
demographic and clinical characteristics of the participants and the
mean scores for the GI Symptom Tracker, GAD-7, PHQ-9 and CFQ-R.
Independent t-tests were used to examine differences in GI symptoms,
anxiety, depression, and HRQoL between adults and adolescents.
Regression analyses were used to analyse the univariable associations
between GI symptoms, anxiety, depression and HRQoL across the two
groups. All regression analyses were adjusted for age, gender, BMI and
lung function.