：Coronary heart disease (CHD) affects a wide population and has a high mortality rate, which seriously threatens the life safety of patients. Early diagnosis and effective treatment can significantly improve the survival and prognosis of the CHD patients. At present, it is mainly judged by detecting various myocardial biomarkers, myocardial movement and coronary blood flow. Stress echocardiography (SE) is one of the commonly used detection methods. It can not only judge the severity of coronary stenosis, but also evaluate myocardial survival and distinguish hibernating myocardium and stunned myocardium. In recent years, it has also emerged in non-coronary heart disease such as artificial valve and hypertrophic cardiomyopathy. This article briefly reviews the principle and classification of SE, and it mainly discusses its important value in the diagnosis and prognosis of CHD.