The esophageal injury after cryoballoon ablation is much rarer than that after radio-frequency ablation.Although it‘s rare, once progressed into atrioesophageal fistula, it could cause a catastrophic iatrogenic tragedy.We report on the occurrence of esophageal injury of A 71-year-old female with symptomatic paroxysmal AF who underwent cryoballoon pulmonary vein isolation. The patient complaint about chest pain exacerbated by swallowing on the postoperative day. Endoscopy detected the esophageal thermal lesions. After 7 days of interventions, the symptoms relieved and retest of endoscopy showed normal esophageal mucosa.We suggest that esophageal protection in cryoballoon ablation is just as important as in RF ablation.