Conclusions
Our meta-analysis suggests that during initial respiratory support, NHFOV can reduce the intubation rate and BPD risk unlike NIPPV. As post-extubation respiratory support, the reintubation rates should be viewed with caution; however, NHFOV decreased the duration of non-invasive ventilation and the incidence of abdominal distention. Further studies are needed to explore the potential benefits of NHFOV for respiratory support in extremely preterm or very low-birth weight infants.

Conflict of Interest Statement

The authors have no conflicts of interest to declare.