Conclusions
Our meta-analysis suggests that during initial respiratory support,
NHFOV can reduce the intubation rate and BPD risk unlike NIPPV. As
post-extubation respiratory support, the reintubation rates should be
viewed with caution; however, NHFOV decreased the duration of
non-invasive ventilation and the incidence of abdominal distention.
Further studies are needed to explore the potential benefits of NHFOV
for respiratory support in extremely preterm or very low-birth weight
infants.
Conflict of Interest
Statement
The authors have no conflicts of interest to declare.