Introduction
Ankylosing spondylitis (AS) is an inflammatory disorder with many
unidentified reasons. The primary involvement in AS cases is an axial
skeleton, defined by joint deformity, stiffness, enthesitis with pain,
and sacroiliac arthritis (1). Systemic inflammation leads to stiffness
and pain in the entheses, spine, and sacroiliac joint resulting in
spinal curvature loss and movement restriction. Advanced disease is
possible to lead to spine and sacroiliac joint fusion, causing a ”bamboo
spine” condition. Enthesopathy, including plantar fasciitis and Achilles
tendonitis, may happen early stage of the disease and result in
structural damage. Peripheral joints, primarily in the lower limbs such
as the hip, and knee, can also be affected (2).
Neuropathic pain can be experienced in AS cases, endorsed by
abnormalities in the brain’s gray matter and neural correlates. The AS
clinical picture includes neuropathic pain, mood deficits, and motor
impairment. Hence, back pain in subjects with AS may be related to
neuropathic pain (3). Also, in AS cases, no precise data showed Axonal
Sensory-Motor Polyneuropathy in these patients. Although, some research
found a correlation between AS and peripheral neuropathy (3-5). Thus,
this case report revealed an AS subject with polyneuropathy, a rare
disease manifestation.