Atorvastatin prevents depressive behavior improving the sphingolipid metabolism and triggering neurovascular coupling via Apolipoprotein EYonggui Song1,#, Meixizi Lai1,#, Zhou Liao1,#, Yali Liu1,3, Liangliang Liao1, Zhentao Zhang1, Genhua Zhu1, Ming Yang1,2, Xiaoquan luo4, Zhifu Ai1,*, Dan Su 1,*