Abbreviations : NP, not performed; IDT, Intradermal testing; DRESS, Drug Rash with Eosinophilia and Systemic Symptoms; GBFDE, Generalised bullous fixed drug eruption; TEN, Toxic epidermal necrolysis; IDT, Intradermal Testing; M, male; F, female; HLA, Human leukocyte antigen; BP, Benzylpenicillin; AMP, Ampicillin; FLX, Flucloxacillin; CFT, Ceftriaxone.
† The immunocompromised category includes patients who are known for any of the following conditions: transplant recipient, haematological or oncological malignancy (in the last 5 y), corticosteroid use of more than 10 mg prednisolone equivalent per day, connective tissue or autoimmune condition, and acquired immunodeficiency syndrome.
‡ Phenotypic scores used as per previously published criteria for SJS/TEN (Alden)[13], DRESS (RegiSCAR) [17]
§ Concentrations : Benzylpenicillin 1mg/ml and 10mg/ml, Ampicillin 25mg/ml, Flucloxacillin 2mg/ml, Ceftriaxone 2.5mg/ml, Cephazolin 1mg/ml
Table 2. Implicated drugs, predictive scores and latency