Study Population
Between July 2007 and February 2011, pregnant women receiving health
service and prenatal care through the Mexican Social Security System
(Instituto Mexicano del Seguro Social –IMSS) were recruited into the
Programming Research in Obesity, Growth, Environment and Social
Stressors (PROGRESS) study. The inclusion criteria were: <20
weeks gestation, at least 18 years old, planned to stay in Mexico City
for the next 3 years, had telephone access, reported no medical history
of heart or kidney disease, no daily alcohol consumption, and no use of
any steroid or anti-epilepsy medications. Following birth, 681
mother-child dyads are actively followed, 605 completed the 48 month
visit and 569 completed the 72 month visits and has the necessary
covariates for analyses. The institutional review boards at the Harvard
School of Public Health, Icahn School of Medicine at Mount Sinai, and
the Mexican National Institute of Public Health approved the procedures
of the study. Women provided written informed consent.