Patient Selection
Between June 2010 and October 2016, a total of 76 patients with primary cervical carcinomas were treated at Sichuan Cancer Hospital with IMRT boast based on ICBT after concurrent chemoradiotherapy. All patients had a large high risk clinical target volume (HR-CTV) volume (>40cc) at the time of brachytherapy, excluding patient with adequate coverage of HR- CTV by optimized ICBT. excluding patient with adequate coverage of HR- CTV by optimized ICBT.
The analysis of the data was performed in October 2020 with a median patient follow up of 85 months (range 47.9-124.2) and a median patient age of 48.9±8.3 years. The initial loco-regional staging included clinical examination under local anesthesia, chest and abdominopelvic computed tomography (CT) and pelvic magnetic resonance imaging (MRI). Positron Emission Tomograpy/Computed Tomography (PET/CT) was not done. The disease was staged according to the 2009 International Federation of Gynecology and Obstetrics (FIGO) classification. Patients with distant metastases (except para-aortic lymph nodes) were excluded from this treatment. All included patients were treated with curative intent. The clinic-pathological features of the patients are given in Table 1.