Staphylococcal Enterotoxins sensitization and response of Omalizumab in severe atopic and non atopic asthma Nicolas Migueres1,2, Anh Poirot1, Nan Zhang ,3,4, Claus Bachert 3,4, Frédéric de Blay1 ,51: Chest Diseases Department, Strasbourg University Hospital, Strasbourg France.2: UMR 7357 Laboratoire des sciences de l’ingénieur, de l’informatique et de l’imagerie ICUBE3: Upper Airways Research Laboratory, Ghent University, Ghent, Belgium4: Division of ENT diseases, CLINTEC, Karolinska Institute, University of Stockholm, Sweden5: EA 3072, Fédération de médecine translationnelle, université de Strasbourg, 67000 Strasbourg, FranceCorresponding author: Nicolas Migueres, nicolas.migueres@chru-strasbourg.frChest Diseases DepartmentNouvel Hôpital CivilHopitaux Universitaires de Strasbourg67093 STRASBOURG CEDEXtel: 00 33 6 07 60 51 86,Total word count ( 570 words)Author Contributions: All investigators contributed to the conception and design of the study. All authors contributed to the acquisition, analysis and interpretation of the data. They provided input into the drafting of the manuscript, critical feedback, and final approval for submission of the manuscript for publication. NM is the guarantor of the final content of the manuscript.The authors have no conflicts of interest to declare.