Enrollment feasibility
Between January 2019 and March 2021, 613 individuals were screened for eligibility (Figure 1). Nine individuals were ineligible because they did not meet study criteria, recruitment closed before screening was done on 204 participants. Of the remaining individuals (n=400), 166 declined to participate and 86 were lost to follow up during the recruitment process. We enrolled 148 of 400 eligible, screened individuals (recruitment 37%; 95%CI 32.2%, 41.9%) over a 23-month period (June 2019-May 2021). Demographic characteristics were overall similar between enrolled versus unenrolled participants (Table S1).