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qianrun Chen
qianrun Chen

Public Documents 2
The Diagnostic and Therapeutic Prospects of Exosomes in Ovarian Cancer
qianrun Chen
Jiayan Shi

qianrun Chen

and 3 more

April 17, 2022
Exosomes are nano-sized vesicles derived from the endosomal system and involved in multitudinous biological and pathological processes. Emerging evidence has demonstrated that exosomes are closely related to the tumorigenesis and progression of ovarian cancer. Ovarian cancer-related exosomes have cell-specific constituents that could be leveraged for diagnosis. Additionally, exosomes are promising to treat ovarian cancer through functioning as delivery systems or participating in immunotherapy or serving as direct targets. In this review, we discussed the association of exosomes in ovarian cancer progression and look forward to the clinical significance of exosomes relevant to diagnosis and treatment.
The progress and prospect of sentinel lymph node mapping in endometrial carcinoma
qianrun Chen
Danhua Ruan

qianrun Chen

and 4 more

June 02, 2022
Sentinel lymph node (SLN) refers to the initial site of the lymphatic drainage from a primary tumor area. Accordingly, sentinel lymph node mapping (SLNM) has been brought up and widely applied to cancer therapy for its illuminating role in clinical lymph node resection. Furthermore, sufficient information to guide surgical pathological staging and adjuvant treatment in endometrial cancer can be rendered by SLNM, hence minimizing surgery injury and reducing the incidence of complications. This review aims to systematically summarize the advances and application prospects of SLNM in endometrial cancer, with an expectation of furnishing reference for the clinical application.

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