Funding information
This work was supported by grants from the National Natural Science Foundation of China (81974410, 81572571, 81630060, 82002769, 81230038), the Major Research Plan of the National Natural Science Foundation of China (91529102), and the Special Funding on Rare Tumors (82141106). The study was also endorsed by the Major Scientific and Technological projects and Key R & D Programs in the Field of Social Development in Hubei Province (No.2021BCA139), and Chinese National Key Plan of Precision Medicine Research (2016YFC0902901, 2016YFC0902900).