Conclusion
Laser ablation for the treatment of VaIN is effective and
well-tolerated, requiring exclusion of malignant lesions of the lower
anogenital tract. The MTLA method was individually carried out according
to the comprehensive status including characteristics of lesions,
high-risk factors and results of surveillance. It was recommended
3~5 number of laser ablation for the HSIL(VaIN2,3) and
2~3 number for the LSIL(VaIN1) patients to obtain a high
pathological cure rate and HR-HPV clearance rate in our study. Larger
areas of lesions and hysterectomy were independent risk factors for
pathological persistence. It was harder for postmenopausal females to
eliminate HR-HPV, and condemn use could protect patients from HR-HPV
infection. Preventing vaginitis was important to reduce the complication
incidence of laser ablation.