Introduction: The laryngeal mask airway (LMA) is an airway management device commonly used during general anesthetics. In this study, a nationwide comprehensive legal database was searched for all medical malpractice cases involving an LMA and analyzed according to the clinical context in which the LMA was implicated. Methods: Cases were identified using Westlaw Edge, a legal database covering 8 million United States federal and over 100 million state dockets. All cases containing the search terms “anesthesiology” and “malpractice” were retrieved, and results were then narrowed to those cases containing “laryngeal mask airway” within their text. Cases were excluded if they did not allege malpractice by an anesthesiologist or the listing was a duplicate case listing. Results: Of the over 500 cases identified, 9 remained for analysis after application of inclusion and exclusion criteria. Three of the cases (33%) involved use of the LMA as a rescue airway device when endotracheal intubation was unsuccessful. Two (22%) alleged aspiration of gastric contents during a general anesthetic with an LMA, and another two (22%) described inadequate ventilation with an LMA that necessitated progression to endotracheal intubation. Discussion: This study helps to better elucidate the role of the LMA in anesthesiology practice by describing related malpractice case outcomes. It is clear from this case series that entry of a defendant verdict does not necessarily indicate that the circumstances surrounding LMA use in that case were congruent with standard of care, as multiple other elements are required to prove medical malpractice. Nevertheless, the analysis of malpractice cases involving LMAs can provide useful clinical insight.