2.3 Data Extraction
A standardised data collection was used to extract the relevant
information from each eligible study as follows: patient
characteristics, such as age, weight, and
laboratory test, ; the study
design, such as research types, quantity of subjects and observations;
dose regimens; OXC formulation; and PPK study information such as data
analysis software and algorithm, model strategies, final PK parameters,
and tested and significant covariates.