The Alveolar soft-part sarcoma (ASPS) involving the lung is mostly metastatic, while the primary ASPS involving the lung occurs more rarely. Herein, we reported on another case of primary ASPS, which might be with the earliest onset reported thus far. In this report, surgery was used to excise the lesion as much as possible, and its combination with chemoradiotherapy and anti-angiogenic agent may provide an important reference for the development of standard treatment or first-line treatment for these children patients. This case may provide an important reference for the development of standard treatment or first-line treatment for these children patients.

Brucellosis is the most common zoonotic infection over the world, caused by bacterial genus brucella. The disease is transmitted rarely via human-to-human transmission. Limited data support vertical transmission of human brucellosis. Herein, we reported a case of congenital brucellosis case. Brucella meliteusis DNA was detected by next-generation sequencing and bacterial identifying under microscope in mother’s placental specimen, which also proved chorioamnionitis. After the first course of rifampicin for 6 weeks and meropenem for 2 weeks, the disease relapsed within 3 weeks. The second course were rifampicin and SMZ/TMP for 8 weeks. The baby was still in following-up.