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Complete resolution of alopecia totalis following chemotherapy treatment for B-cell acute lymphoblastic leukemia
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  • Ariane L'Ecuyer,
  • Rebecca Ronsley,
  • Joseph Lam,
  • David Dix
Ariane L'Ecuyer
British Columbia Children's Hospital

Corresponding Author:ariane.lecuyer@phsa.ca

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Rebecca Ronsley
British Columbia Children's Hospital
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Joseph Lam
British Columbia Children's Hospital
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David Dix
British Columbia Children's Hospital
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Abstract

Alopecia totalis (AT) is a chronic disease that results in non-scarring hair loss of the entire scalp. This results from an autoimmune reaction involving the hair follicles due to genetic and environmental factors. The clinical course of AT is highly unpredictable. There are limited effective durable treatment options. Resolution of alopecia has been reported post-autologous and allogenic hematopoietic stem cell transplantation (HSCT). However, no cases of AT remission following chemotherapy alone have been described. Here, we present a case of complete remission of AT following chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL) in a pediatric patient.
Jul 2022Published in Pediatric Dermatology volume 39 issue 4 on pages 655-656. 10.1111/pde.14977