FIGULRE LEGENDS
Figure 1. (A–C) Microscopic images of bone marrow smears at
onset. Blasts were negative for MPO and 2–3 times the size of small
lymphocytes with a 60–90% nucleus-to-cytoplasm ratio, delicate
chromatin, irregular nuclear contours, prominent nucleoli, and no
cytoplasmic granules. (A) May-Giemsa-stained sample; magnification,
×200. (B) May-Giemsa-stained sample; magnification, ×1000. (C)
MPO-stained sample; magnification, ×400. (D–F) Flow cytometric analysis
before administration of InO, showing a population of blasts expressing
surface CD22 and dim CD45, but lacking CD19.
Figure 2. Clinical course until day +100 post transplantation.
PIR, pre-engraftment immune reaction; GVHD, graft-versus-host disease;
VOD, veno-occlusive disease; SOS, sinusoidal obstruction syndrome; rhTM,
recombinant human soluble thrombomodulin; MTX, methotrexate; mPSL,
methylprednisolone; PSL,
prednisolone; TAC, tacrolimus.