Conclusions
In summary, we constructed the
high-quality chromosome-level genome assembly
for
striped catfish. The phylogenetic position of striped catfish was
revealed by our phylogenomic analysis. Through a genome-wide study, we
observed the tandem triplication of fabp1 gene on the chromosome
10, which may contribute to the high-fat trait in striped catfish.
Comparing the deduced protein sequences of the three fabp1 genes
in striped catfish, we proposed the potential functional effects of
several mutations (especially the R126T) and predicted the
PPAR-selectivity of PPREs. This
high-quality genome assembly will be an improved genetic resource for
further biomedical studies of striped catfish. It will also be a good
reference for genetic improvement of this economically important fish.
Moreover, the detailed
investigations on fabp1 genes in striped catfish may provide new
perspectives
on
molecular breeding for screening individuals with many special traits.