Statistical analysis
Data were analyzed using the JMP software (SAS Institute, Cary, NC, USA). Continuous variables were compared using the independent t-test or the Mann–Whitney U test, while categorical data were analyzed using the chi-squared test. A binary logistic regression approach was adopted to evaluate the independent predictive factors and to create an odds risk of the occurrence of AHRE. A receiver-operating characteristic (ROC) curve was used to analyze the diagnostic accuracy, sensibility, specificity, and predictive value of PWD for new-onset AHRE. For all comparisons, p <0.05 was considered to be statistically significant.