V.2. Laboratory tools
Evidence of IgE responses and eosinophil involvement support a hypersensitivity mechanism, while mycological evidence of fungal persistence is more challenging to obtain (4,6,83,85). Particularly in the case of HSP and ABPA, the determination of mold-specific IgG (A. fumigatus- specific IgG in the case of ABPA) is an additional useful diagnostic tool (95).