Contribution to Authorship
MH and CL performed data curation, investigation and wrote the manuscript together with VS. VS also provided a critical review and text editing. LT performed the data analysis.
MDT was the project administrator, conceived the idea and designed the study. MDT, FP and AG provided validation and visualization of the final manuscript.

Details of Ethics Approval

This study was performed according to the principles of the Declaration of Helsinki (2013) and was approved by the ethics committee of Careggi University Hospital (approval date 18/12/2020, reference number 18008_bio).