Lynch syndrome (LS) is the most common hereditary colon cancer syndrome caused by germline mutations in mismatch repair (MMR) genes. In this series, we outline 3 pediatric patients who presented with vague symptoms due to colorectal cancer who were eventually diagnosed with Lynch syndrome with multiple gene mutations. The diagnosis of colorectal cancer in pediatrics warrants timely recognition, inclusion of Lynch syndrome in the differential diagnosis, multi-gene testing, and genetic counseling for the patient and family.