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Immunotherapy beyond cellular therapy in Follicular Lymphoma: A case of complete remission after failure of two CAR-T
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  • Adam Kase,
  • Mohamed Kharfan Dabaja ,
  • Andrew Donaldson,
  • Jamie Elliott,
  • Taimur Sher
Adam Kase
Mayo Clinic in Florida

Corresponding Author:kase.adam@mayo.edu

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Mohamed Kharfan Dabaja
Mayo Clinic Hospital Jacksonville
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Andrew Donaldson
Mayo Clinic in Florida
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Jamie Elliott
Mayo Clinic in Florida
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Taimur Sher
Mayo Clinic in Florida
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Abstract

Patients with relapsed follicular lymphoma who do not respond to CAR-T have a poor outcome. We present a case of refractory follicular lymphoma who relapsed after two CAR-T infusions and achieved a complete remission after treatment with obinutuzumab and lenalidomide. This represents a promising treatment option in the post-CAR-T setting.
13 Jan 2022Submitted to Clinical Case Reports
17 Jan 2022Assigned to Editor
17 Jan 2022Submission Checks Completed
30 Jan 2022Reviewer(s) Assigned
09 Feb 2022Review(s) Completed, Editorial Evaluation Pending
16 Feb 2022Editorial Decision: Accept
Apr 2022Published in Clinical Case Reports volume 10 issue 4. 10.1002/ccr3.5572