Aortic valve reconstruction surgery. Operative results from a Peruvian
Cohort Running tittle: AVrec Surgery
Abstract
Background Aortic valve replacement is the gold standard
treatment for severe symptomatic aortic valve disease. Recently, aortic
valve reconstruction surgery (Ozaki procedure) emerges as a surgical
alternative with good results in the medium term. Methods We
retrospectively analyzed 38 patients who underwent aortic valve
reconstruction surgery between January 2018 and June 2020 in a national
reference center in Lima, Peru. The median age was 62 years,
interquartile range 25. The main indication for surgery was aortic valve
stenosis (63.1%), in most cases due to bicuspid valve (19 patients,
50%). Twenty-two (58%) patients had another pathology with surgical
indication associated to AV disease, 8(21%) had dilatation of the
ascending aorta with indication for replacement. Results One
in-hospital death occurred (1/38, 2.6%) due to perioperative myocardial
infarction. There was a significant reduction in the medians of the peak
(66mmHg, CI95%=52.5-81.3 vs 15mmHg, CI95%=12.1-17.5,
p<0.0001) and mean (41mmHg CI95%=31.8-50.1 vs 8mmHg,
CI95%=6.0-9.6, p<0.0001) aortic valve gradients when we
compared baseline characteristics with first 30-days results. In an
average of 19 (±8.9) months of follow-up, survival, reoperation-free
survival for valve dysfunction, and survival free of AV
insufficiency> II were 94.6%, 94.6% y 91.7%,
respectively. Significant reduction in the medians of the peak (66mmHg,
CI95%=52.5-81.3 vs 14mmHg, CI95%=10.9-17.6, p<0.0001) and
mean (41mmHg CI95%=31.8-50.1 vs 7mmHg, CI95%=5.2-9.1,
p<0.0001) aortic valve gradients were maintained.
Conclusions Mid-term outcome follow-up of aortic valve
reconstruction surgery showed optimal results in term of mortality,
reoperation free survival and hemodynamic characteristics of the
neo-aortic valve.