Incidence of severe perineal laceration
Six trials involving 2180 women were included in this outcome, 2143
women contributed data. The result of meta-analysis indicated that women
in lubricant group had no statistically difference in the incidence of
severe perineal laceration when compared with those in standard care
group (RR 0.3, 95%CI 0.05 to 1.88; I2=0%; low due to
serious risk of bias and serious imprecision) (Table 1, Figure S19).
Subgroup analysis showed that there was not significant subgroup effect
between lubricants type subgroups (Pinteraction=0.93) (Figure S20).
When analyzed based on parity, there was not significant in the
incidence of severe perineal laceration in lubricant group versus
standard care group for nulliparous women (RR 0.28, 95%CI 0.23 to 2.69;
I2=0%) (Figure S21). There was insufficient data to
perform subgroup analysis for this outcome for multiparous women.