Introduction
Secondary infections or co-infections are commonly identified in severe influenza and also other severe respiratory viral infections with high mortality and morbidity rate [1]. Co-infection between SARS-CoV-2 and other pathogens have become another serious threat in the treatment of patients which should not be neglected [2]. These co-pathogens are including bacteria, such as Streptococcus pneumoniae andStaphylococcus aureus, fungal pathogens includingAspergillus or Mucorales species and also viruses such as influenza, and rhinovirus/enterovirus [3]. Herein we report the first case of concomitant aspergillosis, mucormycosis, cytomegalovirus (CMV) pneumonia and also klebsiella pneumoniae empyema as the complication of COVID-19 infection who had a favorable clinical outcome.