Parameter |
Gallic acid |
Methyl gallate |
Propyl gallate |
Octyl
gallate |
Dodecyl gallate |
Stearyl gallate |
RSA % |
|
|
|
|
|
|
10 µM |
28.08 ± 0.59 b |
21.16 ± 0.68 a |
20.68 ± 1.06 a |
20.06 ± 0.76
a |
20.18 ± 1.17 a |
19.87 ± 1.09 a |
20 µM |
36.45 ± 0.79 c |
29.05 ± 0.79 ab |
29.16 ± 0.62 b |
27.78 ± 0.80
ab |
28.69 ± 1.06 ab |
27.01 ± 0.72 a |
30 µM |
49.74 ± 0.49 b |
40.32 ± 0.46 a |
40.27 ± 0.90 a |
39.52 ± 1.24
a |
39.16 ± 0.46 a |
38.66 ± 0.65 a |
40 µM |
63.16 ± 1.06 c |
50.24 ± 0.92 ab |
51.40 ± 0.55 b |
50.11 ± 0.60
ab |
49.87 ± 0.59 ab |
49.17 ± 0.73 a |
50 µM |
75.09 ± 0.63 c |
64.17 ± 1.23 ab |
65.56 ± 0.74b |
63.77 ± 0.58
ab |
63.05 ± 0.79 a |
62.39 ± 1.13 a |
IC50 (µM) |
29.58 ± 0.36 a |
38.40 ± 0.44 bc |
37.66 ±
0.59 b |
38.88 ± 0.41 bc |
39.17 ± 0.89 bc |
39.87 ± 0.72
c |
BCB % |
|
|
|
|
|
|
10 µM |
17.36 ± 0.29 a |
20.22 ± 0.45 b |
20.56 ± 0.93 b |
22.64 ± 0.27
c |
25.06 ± 0.49 d |
18.07 ± 0.17 a |
20 µM |
25.02 ± 0.27 a |
28.07 ± 0.49 b |
27.94 ± 0.66 b |
30.21 ± 0.15
c |
34.72 ± 0.75 d |
26.88 ± 0.45 b |
30 µM |
32.88 ± 0.22 a |
35.09 ± 0.31 b |
36.16 ± 0.76 c |
36.87 ± 0.13
c |
42.12 ± 0.15 d |
32.61 ± 0.11 a |
40 µM |
43.75 ± 0.29 b |
44.28 ± 0.73 b |
46.37 ± 0.72 c |
48.06 ± 0.34
d |
52.11 ± 0.11 e |
40.39 ± 0.22 a |
50 µM |
58.46 ± 0.45 ab |
60.34 ± 0.25 c |
59.55 ± 0.65 bc |
63.60 ±
0.31 d |
69.08 ± 0.11 e |
58.07 ± 0.87 a |
IC50 (µM) |
44.37 ± 0.45 d |
42.85 ± 0.12 c |
42.32 ±
0.13 c |
39.75 ± 0.21 b |
35.10 ± 0.32 a |
45.82 ± 0.35 e |
OSI (h) |
4.72 ± 0.15 a |
5.32 ± 0.45 b |
6.20 ± 0.16 d |
5.81 ± 0.14 c |
5.73 ± 0.05 c |
5.34 ± 0.03 b |
log P |
-0.47 ± 0.06 a |
0.66 ± 0.05 b |
0.82 ± 0.03 c |
0.97 ± 0.07 d |
1.24 ± 0.04 e |
1.65 ± 0.07 f |