Parameter Gallic acid Methyl gallate Propyl gallate Octyl gallate Dodecyl gallate Stearyl gallate
RSA %
10 µM 28.08 ± 0.59 b 21.16 ± 0.68 a 20.68 ± 1.06 a 20.06 ± 0.76 a 20.18 ± 1.17 a 19.87 ± 1.09 a
20 µM 36.45 ± 0.79 c 29.05 ± 0.79 ab 29.16 ± 0.62 b 27.78 ± 0.80 ab 28.69 ± 1.06 ab 27.01 ± 0.72 a
30 µM 49.74 ± 0.49 b 40.32 ± 0.46 a 40.27 ± 0.90 a 39.52 ± 1.24 a 39.16 ± 0.46 a 38.66 ± 0.65 a
40 µM 63.16 ± 1.06 c 50.24 ± 0.92 ab 51.40 ± 0.55 b 50.11 ± 0.60 ab 49.87 ± 0.59 ab 49.17 ± 0.73 a
50 µM 75.09 ± 0.63 c 64.17 ± 1.23 ab 65.56 ± 0.74b 63.77 ± 0.58 ab 63.05 ± 0.79 a 62.39 ± 1.13 a
IC50 (µM) 29.58 ± 0.36 a 38.40 ± 0.44 bc 37.66 ± 0.59 b 38.88 ± 0.41 bc 39.17 ± 0.89 bc 39.87 ± 0.72 c
BCB %
10 µM 17.36 ± 0.29 a 20.22 ± 0.45 b 20.56 ± 0.93 b 22.64 ± 0.27 c 25.06 ± 0.49 d 18.07 ± 0.17 a
20 µM 25.02 ± 0.27 a 28.07 ± 0.49 b 27.94 ± 0.66 b 30.21 ± 0.15 c 34.72 ± 0.75 d 26.88 ± 0.45 b
30 µM 32.88 ± 0.22 a 35.09 ± 0.31 b 36.16 ± 0.76 c 36.87 ± 0.13 c 42.12 ± 0.15 d 32.61 ± 0.11 a
40 µM 43.75 ± 0.29 b 44.28 ± 0.73 b 46.37 ± 0.72 c 48.06 ± 0.34 d 52.11 ± 0.11 e 40.39 ± 0.22 a
50 µM 58.46 ± 0.45 ab 60.34 ± 0.25 c 59.55 ± 0.65 bc 63.60 ± 0.31 d 69.08 ± 0.11 e 58.07 ± 0.87 a
IC50 (µM) 44.37 ± 0.45 d 42.85 ± 0.12 c 42.32 ± 0.13 c 39.75 ± 0.21 b 35.10 ± 0.32 a 45.82 ± 0.35 e
OSI (h) 4.72 ± 0.15 a 5.32 ± 0.45 b 6.20 ± 0.16 d 5.81 ± 0.14 c 5.73 ± 0.05 c 5.34 ± 0.03 b
log P -0.47 ± 0.06 a 0.66 ± 0.05 b 0.82 ± 0.03 c 0.97 ± 0.07 d 1.24 ± 0.04 e 1.65 ± 0.07 f