1.3.6 Risk score adjustments
We performed several adjustments to score points and cutoff values based
on the primary regression analysis in panel A, and optimized these
adjustments based on results from panel B.
After multiple adjustments, we were able to develop an optimized and
balanced QTc-prolongation risk score with a cutoff of 5 points as
demonstrated in table 4 below.
Table 4. Optimized risk score