Risk factor
Patients (%) N=100 Custom alerts (%) N=521
Custom alerts with QTc Prolongation* (%)
Age ≥ 65 years
49 (49%) Mean=61, Median=64 240 (46%) Mean=61, Median=64
88 (37%)
Female sex 50 (50%) 269 (52%) 58 (22%)
BMI ≥ 30 kg/m2
34 (34%) Mean=29, Median=28 210 (40%) Mean=29, Median=28
70 (33%)
Ischemic cardiomyopathy and/or hypertension 52 (52%) 297 (57%) 35 (12%)
Arrhythmia 12 (12%) 75 (14%) 27 (36%)
Thyroid disturbances 29 (29%) 152 (29%) 36 (24%)
Liver failure
3 (3%)
17 (3%)
17 (100%) 11 (65%) had higher baseline ECG
Neurological disorders 0 (0%) 0 (0%) 0 (0%)
Diabetes 41 (41%) 221 (41%) 57 (26%)
Potassium ≤ 3.5 mmol/L
23 (23%)
83 (16%) Mean=3.75, Median=4
29 (35%)
Calcium < 2.15 mmol/L
21 (21%)
81 (16%) Mean=9, Median=9.1
17 (21%)
CRP > 5 mg/L
16 (16%)
97 (19%) Mean=89, Median=82 402 missing values
35 (36%)
eGFR ≤ 30 ml/min
7 (7%)
48 (9%) Mean=89, Median=90
5 (10%)
List 1 QT-drug CredibleMeds 82 (82%) 1-4 drugs/patient 386 (74%) 105 (27%)
List 2 QT-drug CredibleMeds 62 (62%) 1-3 drugs/patient 235 (45%) 52 (22%)
List 3 QT-drug CredibleMeds 75 (75%) 1-6 drugs/patient 397 (76%) 116 (29%)
Prolonged QTc (≥450(♂)/470(♀) ms) on previous ECG 15 (15%) 82 (16%) 45 (55%)