Continuous glucose monitoring
All study participants inserted and wore a CGM sensor on the back of
either their right or left upper arm, without any over-bandage for up to
14 days. Participants in the blinded group wore the sensor for 14 days
without a reader. Neither the participant nor the study team members had
access to the data recorded by the CGM sensor during this time. At the
end of the 14-days the participant were to scan the sensor using the
blinded-reader by themselves or there were assisted by a clinical
research coordinator in the clinic, and the data from the reader was
downloaded to a research computer. Participants in the unblinded group
wore the sensor for 14 days with an open reader which provided them
glucose readings each time the sensor was scanned. The participants were
requested to upload their glucose readings every 8 hours, or at least
three times a day where possible using the reader provided, but were
allowed to scan their glucose levels as often as they wanted. After each
14-day wear- period all participants were asked to dispose of the used
sensor and received a new sensor according to the study clinic visit
schedule (Figure S1). Apart from the type of CGM sensors allocated, all
participants were assessed in the same way.