Figure 2| Computational model predicting guide RNA activities
(a) (b) The schematic of datasets and algorithm used
(c) ROC curves comparing the predictive power of our model and deepCpf1.
(d) A quantization of (c) and the bar shows the mean ±s.d. between
predicted and measured guide activity scores (n=10)
(e) Comparison of the different models. A smaller scale library of 6,265
guide RNAs was processed by each model, and the top 1,000 scored ones
were chosen as an efficient group, in comparison to bottom 1,000 ones as
an inefficient group. Their corresponding experimental activity scores
were compared.
(f) The former library was re-chosen into high score and low score group
by measured guide RNA activities (1,000 members from 6,265).