Figure 3 |The top sequence features for predicting guide RNA activities
(a)The features for adjacent dimers of guide RNAs are plotted as heatmaps based on their position in seed region, and positive coefficients suggest positive contributions to guide RNA activity.
(b)The features for adjacent trimers of guide RNAs are plotted as heatmaps based on their position in seed region, and positive coefficients suggest positive contributions to guide RNA activity.
(c) The features for adjacent nucleotides of guide RNAs are plotted as columns based on their position in seed region, and positive coefficients suggest positive contributions to guide RNA activity.
(d) T7EI analysis of targeted indel frequencies induced by the 6 guide RNAs with different sequence features.