Figure 4. Tshr mutations in Western European common vole
populations. Manhattan-type plots (-log10(p ))
for the sequenced Tshr region for (A) geographical distance, (D)
latitude, (G) longitude, (J) altitude and (M) predicted critical
photoperiod (pCPP). Grey bars indicate Benjamini-Hochberg adjusted
p-values, black bars indicate R2-values. SNPs that
meet the threshold for significant correlations (p < 0.05)
cross the red dashed line. Pairwise difference in SNP frequency for two
representative mutations (SNP-158 and SNP126) related to (B,C) pairwise
geographical distance, (E,F) pairwise latitudinal difference, (H,I)
pairwise longitudinal difference, (K,L) pairwise altitudinal difference
and (N,O) pairwise difference in pCPP. Significant correlations are
indicated by linear regression lines. All statistic results of linear
models for SNP frequency related to environmental proxies can be found
in Table S6.