Franklin
Franklin by Genoox (https://franklin.genoox.com) (Genoox) connects clinicians, genetic counselors, and healthcare organizations, enabling its users to make impactful discoveries using the most advanced genomic tools and applications. The power of the Franklin community provides actionable insights from the largest real-time real-life genomic database serving professionals at the point of care.
Franklin is built on top of an advanced AI-based interpretation engine and provides an automated workflow from raw sequencing data (FASTQ/VCF) to a short list of candidate variants for a final clinical report. The interpretation engine supports multiple genetic applications including rare diseases, oncology, hereditary cancer, and carrier screening. The engine provides in-depth variant evidence, literature and text-mining evidence, automated ACMG-based classification for SNPs and CNVs, and a wealth of annotations and assessment tools.
Franklin community members can share their own evidence and insights regarding a variant or a gene with the rest of the community, as well as start a discussion on a case/variant level, to reach a consensus. In addition, members are able to contact other members in an anonymous way to inquire about a specific variant of interest that surfaced during their analysis. This feature assists in resolving uncertainties, and providing more accurate classification.
Franklin is used today by over 1,700 health organizations and is available at no charge. The platform is widely used in hospitals, laboratories, and medical facilities throughout 44 markets across the globe.