World Health Organization Global Air Quality Guideline Recommendations: Executive SummaryAnna Goshua1, Cezmi Akdis2, Kari C. Nadeau3,4 1Stanford School of Medicine, Stanford, CA, USA2Swiss Institute of Allergy and Asthma Research (SIAF), University Zurich, Davos, Switzerland3Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, CA, USA4Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Stanford University, Stanford, CA, USACorresponding Author: Kari C. Nadeau, Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford University, Stanford, CA, USA; Email: knadeau@stanford.eduConflict of Interest: Dr Cezmi Akdis reports research grants from Allergopharma, Idorsia, Swiss National Science Foundation, Christine Kühne-Center for Allergy Research and Education, European Commission’s Horison’s 2020 Framework Programme “Cure”, Novartis Research Institutes, Astra Zeneca, research grants and advisory board from Glaxo Smith-Kline, Sanofi/Regeneron, Scibase, Novartis, and is Editor-in-Chief of Allergy. All other authors declare no conflict of interest.Text Word Count: 1243Abstract Word Count: 147Figure/Table Count: 2Reference Count: 9

There is increasing understanding, globally, that climate change and increased pollution will have a profound and mostly harmful effect on human health. This review brings together international experts to describe both the direct (such as heat waves) and indirect (such as vector-borne disease incidence) impacts of climate change depending on their vulnerability (i.e., diseases) on an international, economic, political and environmental context. This unique review also expands on these issues to address a third category of potential longer-term impacts on global health: famine, population dislocation, and environmental justice and education. This scholarly resource explores these issues fully, linking them to global health in urban and rural settings in developed and developing countries. The review finishes with a practical discussion of action that health professionals around the world in our field can yet take.